C-N Rail says its crews are responding after 14 railcars loaded with potash derailed near Rayleigh.
Spokesperson Scott Brown says there were no dangerous goods involved and no leaks, injuries or fires reported.
It's not clear what time the train derailed, but witnesses have said it happened between 7 and 10 Wednesday morning.
This is the second train derailment in the Kamloops area this month -- and comes after five railcars carrying fuel went off the tracks east of Ashcroft on Labour Day Monday.