Omicron's latest subvariant BA.2.12.1 proves virus not declining: Report
Darpan News Desk IANS, 02 May, 2022 11:25 AM
New York, May 2 (IANS) Omicron's latest subvariant BA.2.12.1, responsible for about one-fourth of Covid-19 cases in the US, shows that the virus is not showing any signs of decline even over two years after it was first detected in humans.
BA.2.12.1 has also been detected in Australia and New Zealand.
Preliminary research suggests it is about 25 per cent more transmissible than the BA.2 subvariant that is currently dominant nationally, according to the Centers for Disease Control and Prevention.
According to virologists, although the SARS-CoV-2 virus has repeatedly changed its structure and chemistry, it still has abundant evolutionary space to explore, Washington Post reported.
While existing vaccination can still reduce the risk of severe Covid disease, the variants can evade many of the neutralising antibodies that are the immune system's front line of defence.
"It's evolving at a fairly rapid rate. I do think we need to aggressively consider whether we should update vaccines, and do it soon," Jesse Bloom, a computational biologist at the Fred Hutchinson Cancer Research Center in Seattle was quoted as saying.
"The evolution is much more rapid and expansive than we initially estimated," added Michael Osterholm, infectious-disease expert at the University of Minnesota.
"Every day I wake up, I fear there will be a new subvariant that we will have to consider. . . We're seeing sub-variants of sub-variants," he added.
Other mutations include BA.4 and BA.5, recently identified by scientists in South Africa. It has led to a fresh wave of Covid in the country.
Besides South Africa, the sub variants have also been detected in more than 20 countries including Australia, Austria, Belgium, China, Israel, Denmark, France, Germany, Pakistan, UK, US and Switzerland.
Apart from mutation, the virus has another trick up its sleeve: recombination. It happens when two distinct strains infect a single host simultaneously and their genes become entangled, the Post reported.
The recombination process is the origin of what's known as Omicron XE. That recombinant probably emerged from a person co-infected with the original Omicron variant and the BA.2 subvariant.
It was always possible in theory, but the identification of actual recombinants provides "proof of concept," Jeremy Luban, a virologist at the University of Massachusetts Medical School was quoted as saying.
The worst-case scenario would be the emergence of a variant or recombinant that renders current vaccines largely ineffective at blocking severe disease. But so far, that hasn't happened. And no "recombinant" has spread like Omicron or other recent variants and sub-variants, the report said.
In a statement on Friday, the U.N. health agency said the new scientific group would provide the WHO with an independent analysis of the work done to date to pinpoint the origins of COVID-19 and to advise the agency on necessary next steps. The experts will also provide guidance on critical issues regarding the potential emergence of other viruses capable of triggering outbreaks, such as MERS and Ebola.
During their first press conference on Tuesday the Taliban pressed the right button-backing women's rights. But their promise of protecting women's rights had an important nuance: Women will enjoy freedoms but within the ambit of "Islamic law" .
A contingent of persons from the Hindu and Sikh communities who are stranded in Afghanistan were provided reassurance of safety by the Taliban, media reports said. Over 300 Hindus and Sikhs are reportedly taking shelter at the Karte Parwan Gurudwara in Kabul.
We need humanitarian supplies. The refugee situation we updated you with last week and the week before has only deteriorated. We have 300,000 internal refugees and 80,000 children who are without shelter and food. Where we were short of supplies, now we are out.
Nikita Ishchenko, a spokesman for the Russian Embassy in Kabul, was quoted as saying by RIA: "Four cars were full of money, they tried to stuff another part of the money into a helicopter, but not all of it fit. And some of the money was left lying on the tarmac."
Fully vaccinated U.S. citizens and permanent residents can now enter Canada for non-essential purposes for the first time since March 2020, when the COVID-19 pandemic forced the two countries to severely curtail travel.
