Omicron's latest subvariant BA.2.12.1 proves virus not declining: Report
Darpan News Desk IANS, 02 May, 2022 11:25 AM
New York, May 2 (IANS) Omicron's latest subvariant BA.2.12.1, responsible for about one-fourth of Covid-19 cases in the US, shows that the virus is not showing any signs of decline even over two years after it was first detected in humans.
BA.2.12.1 has also been detected in Australia and New Zealand.
Preliminary research suggests it is about 25 per cent more transmissible than the BA.2 subvariant that is currently dominant nationally, according to the Centers for Disease Control and Prevention.
According to virologists, although the SARS-CoV-2 virus has repeatedly changed its structure and chemistry, it still has abundant evolutionary space to explore, Washington Post reported.
While existing vaccination can still reduce the risk of severe Covid disease, the variants can evade many of the neutralising antibodies that are the immune system's front line of defence.
"It's evolving at a fairly rapid rate. I do think we need to aggressively consider whether we should update vaccines, and do it soon," Jesse Bloom, a computational biologist at the Fred Hutchinson Cancer Research Center in Seattle was quoted as saying.
"The evolution is much more rapid and expansive than we initially estimated," added Michael Osterholm, infectious-disease expert at the University of Minnesota.
"Every day I wake up, I fear there will be a new subvariant that we will have to consider. . . We're seeing sub-variants of sub-variants," he added.
Other mutations include BA.4 and BA.5, recently identified by scientists in South Africa. It has led to a fresh wave of Covid in the country.
Besides South Africa, the sub variants have also been detected in more than 20 countries including Australia, Austria, Belgium, China, Israel, Denmark, France, Germany, Pakistan, UK, US and Switzerland.
Apart from mutation, the virus has another trick up its sleeve: recombination. It happens when two distinct strains infect a single host simultaneously and their genes become entangled, the Post reported.
The recombination process is the origin of what's known as Omicron XE. That recombinant probably emerged from a person co-infected with the original Omicron variant and the BA.2 subvariant.
It was always possible in theory, but the identification of actual recombinants provides "proof of concept," Jeremy Luban, a virologist at the University of Massachusetts Medical School was quoted as saying.
The worst-case scenario would be the emergence of a variant or recombinant that renders current vaccines largely ineffective at blocking severe disease. But so far, that hasn't happened. And no "recombinant" has spread like Omicron or other recent variants and sub-variants, the report said.
The searing parallels that bookend the two decades — shaken commanders-in-chief promising retribution for a devastating suicide attack; triumphant Taliban militants in Afghanistan and a military transport fleeing Kabul — might suggest little has changed. Of course, since Sept. 11, virtually everything has.
Mu, also known as B.1.621, was first identified from Colombia in January this year. Infections from Mu have since been recorded in South America and Europe. Based on the latest round of assessments, B.1.621 was classified as a VOI on 30 August 2021 and given the WHO label "Mu".
The militant group's metamorphosis from rag-tag guerrilla force to highly professional, impressively equipped army has been at the expense of Western taxpayers, the report said.
"Russia should be concerned about the rise of the Taliban. The country will become a terrorist hub that will endanger Central Asia and Russia itself," Fahim Dashty told The Moscow Times by phone from the Panjshir Valley, where his resistance group has gathered as the country's last holdout against the Taliban.
On Thursday evening, a suicide bombing rocked a gate of the airport where a crashing crowd was waiting for evacuation flights, and later another explosion hit the nearby Baron Camp, a former coalition base.
In his first comments on Kashmir, Taliban spokesman Zabiullah Mujahid has said that Pakistan and India should sit together to resolve all their outstanding issues because both are neighbours and their interests are linked to each other.
