Close X
Monday, November 11, 2024
ADVT 
Health

New treatment for gum disease in diabetics

Darpan News Desk IANS, 01 Aug, 2014 09:10 AM
    Going to the dentist may not be fun but for those with periodontal disease related to type-two diabetes, a new research may bring back their smile.
     
    Scientists have found that B cells - one of the most important blood cells involved in the human immune response - are shown to promote inflammation and bone loss in type-two diabetes-associated periodontal disease.
     
    The treatments that manipulate the responses of B cells may treat or prevent the symptoms of type-two diabetes and periodontitis or pyorrhea simultaneously.
     
    "Our study paves the way for the development of novel therapeutics which aim to simultaneously treat both type-two diabetes and its complications," said Min Zhu, a researcher from department of microbiology at Boston University's school of medicine.
     
    To make this discovery, scientists used a mouse model of periodontal disease and applied it to two groups.
     
    The first group had a genetic alteration that knocked out all B cells.
     
    The second group had normal B cell levels.
     
    When fed a low-fat diet, without development of obesity and type-two diabetes, both groups demonstrated a similar extent of oral bone loss and inflammation.
     
    However, when they were fed a high-fat diet, oral bone loss and inflammation occurred in the normal group with B cells but did not develop in the group that had a genetic alteration that knocked out all B cells.
     
    This suggests that the B cell-response might be a viable target for pharmacological intervention in both type-two diabetes and periodontal disease, as well as potentially in other type-two diabetes complications.
     
    The research was published in the Journal of Leukocyte Biology.

    MORE Health ARTICLES

    Brain next frontier to treat obesity

    Brain next frontier to treat obesity
    Therapies aimed at areas of the brain responsible for memory and learning could lead to better treatment of obesity and dementia, says a study...

    Brain next frontier to treat obesity

    About 13 percent new mothers avoid sex

    About 13 percent new mothers avoid sex
    Have you rejected love-making calls from your hubby after childbirth? Take heart as you have not committed a sin....

    About 13 percent new mothers avoid sex

    Monitor pulse after stroke to avoid second

    Monitor pulse after stroke to avoid second
    Regularly monitoring your pulse after a stroke or the pulse of a loved one who has experienced a stroke can prevent a second stroke....

    Monitor pulse after stroke to avoid second

    Condom that fights sexually-transmitted diseases

    Condom that fights sexually-transmitted diseases
    Imagine a condom that not only stops pregnancy but also kills germs that can lead to sexually transmitted diseases (STDs)....

    Condom that fights sexually-transmitted diseases

    Impulsive behaviour linked to brain connectivity

    Impulsive behaviour linked to brain connectivity
    In what could help better understand behavioural problems and social adaptation difficulties in children, researchers have found that patterns of brain connectivity...

    Impulsive behaviour linked to brain connectivity

    Vitamin D deficiency increases schizophrenia risk

    Vitamin D deficiency increases schizophrenia risk
    Individuals with Vitamin D deficiency are twice as likely to be diagnosed with schizophrenia as compared to those who have sufficient levels of the...

    Vitamin D deficiency increases schizophrenia risk