Close X
Thursday, November 28, 2024
ADVT 
Health

New treatment for gum disease in diabetics

Darpan News Desk IANS, 01 Aug, 2014 09:10 AM
    Going to the dentist may not be fun but for those with periodontal disease related to type-two diabetes, a new research may bring back their smile.
     
    Scientists have found that B cells - one of the most important blood cells involved in the human immune response - are shown to promote inflammation and bone loss in type-two diabetes-associated periodontal disease.
     
    The treatments that manipulate the responses of B cells may treat or prevent the symptoms of type-two diabetes and periodontitis or pyorrhea simultaneously.
     
    "Our study paves the way for the development of novel therapeutics which aim to simultaneously treat both type-two diabetes and its complications," said Min Zhu, a researcher from department of microbiology at Boston University's school of medicine.
     
    To make this discovery, scientists used a mouse model of periodontal disease and applied it to two groups.
     
    The first group had a genetic alteration that knocked out all B cells.
     
    The second group had normal B cell levels.
     
    When fed a low-fat diet, without development of obesity and type-two diabetes, both groups demonstrated a similar extent of oral bone loss and inflammation.
     
    However, when they were fed a high-fat diet, oral bone loss and inflammation occurred in the normal group with B cells but did not develop in the group that had a genetic alteration that knocked out all B cells.
     
    This suggests that the B cell-response might be a viable target for pharmacological intervention in both type-two diabetes and periodontal disease, as well as potentially in other type-two diabetes complications.
     
    The research was published in the Journal of Leukocyte Biology.

    MORE Health ARTICLES

    Influenza patients in US wrongly prescribed antibiotics?

    Influenza patients in US wrongly prescribed antibiotics?
    Taking antibiotics does not help patients suffering from influenza, a viral disease, but nearly 30 percent of the flu patients who were treated during the 2012-2013 influenza season in the US may have been prescribed unnecessary antibiotics instead of antiviral therapy, says a study.

    Influenza patients in US wrongly prescribed antibiotics?

    Food strikes obese women with learning impairment

    Food strikes obese women with learning impairment
    In what could result in specific behavioural interventions to treat obesity, researchers have found that obese women are better able to identify cues that predict monetary rewards than those that predict food rewards.

    Food strikes obese women with learning impairment

    Injection to control diabetes without side effects

    Injection to control diabetes without side effects
    Dealing with diabetes could soon be a lot easier as researchers have developed an injection that can restore blood sugar levels to normal for more than two days without any side effects.

    Injection to control diabetes without side effects

    'Include men in breast cancer trials'

    'Include men in breast cancer trials'
    Men may find it hard to report anything in their breast, even if it is a lump, but the fact is breast cancer is not exclusive to women and though the proportion is small, men too can have it.

    'Include men in breast cancer trials'

    Even 'third-hand' smoke kills

    Even 'third-hand' smoke kills
    Have you finally amended your habits and stopped smoking inside the house to protect your kids from exposure to second-hand smoke? That may not be good enough!

    Even 'third-hand' smoke kills

    Why women shy away from joining science stream

    Why women shy away from joining science stream
    In what could be one of the reasons why women shy away from joining science stream, a survey reveals that many young scientists have suffered sexual harassment or sexual assault while at work in the field.

    Why women shy away from joining science stream