Close X
Thursday, November 28, 2024
ADVT 
Health

New treatment for gum disease in diabetics

Darpan News Desk IANS, 01 Aug, 2014 09:10 AM
    Going to the dentist may not be fun but for those with periodontal disease related to type-two diabetes, a new research may bring back their smile.
     
    Scientists have found that B cells - one of the most important blood cells involved in the human immune response - are shown to promote inflammation and bone loss in type-two diabetes-associated periodontal disease.
     
    The treatments that manipulate the responses of B cells may treat or prevent the symptoms of type-two diabetes and periodontitis or pyorrhea simultaneously.
     
    "Our study paves the way for the development of novel therapeutics which aim to simultaneously treat both type-two diabetes and its complications," said Min Zhu, a researcher from department of microbiology at Boston University's school of medicine.
     
    To make this discovery, scientists used a mouse model of periodontal disease and applied it to two groups.
     
    The first group had a genetic alteration that knocked out all B cells.
     
    The second group had normal B cell levels.
     
    When fed a low-fat diet, without development of obesity and type-two diabetes, both groups demonstrated a similar extent of oral bone loss and inflammation.
     
    However, when they were fed a high-fat diet, oral bone loss and inflammation occurred in the normal group with B cells but did not develop in the group that had a genetic alteration that knocked out all B cells.
     
    This suggests that the B cell-response might be a viable target for pharmacological intervention in both type-two diabetes and periodontal disease, as well as potentially in other type-two diabetes complications.
     
    The research was published in the Journal of Leukocyte Biology.

    MORE Health ARTICLES

    Busiest hospital best for emergency patients

    Busiest hospital best for emergency patients
    When a medical emergency strikes, instinct tells us to go to the nearest hospital quickly.

    Busiest hospital best for emergency patients

    Common cholesterol drug linked to death risk

    Common cholesterol drug linked to death risk
    Niacin, a common cholesterol drug for 50 years, should no longer be prescribed owing to potential increased risk of death, dangerous side effects and no benefit in reducing heart attacks and strokes, researchers said.

    Common cholesterol drug linked to death risk

    Eat leafy vegetables to reset biological clock

    Eat leafy vegetables to reset biological clock
    Lipoic acid, found at higher levels in organ meats and leafy vegetables such as spinach and broccoli, may help reset and synchronise circadian rhythms or the "biological clock" found in most life forms, says a study.

    Eat leafy vegetables to reset biological clock

    Divorce can lead to high blood pressure

    Divorce can lead to high blood pressure
    Just had a divorce and facing persistent sleep problems? Check your blood pressure as you may be at the risk of potentially harmful increase in blood pressure, says a study.

    Divorce can lead to high blood pressure

    True happiness lies in your DNA

    True happiness lies in your DNA
    Looking for eternal happiness? Try to match the DNA of Danish people.

    True happiness lies in your DNA

    Statins may increase life of diabetics: Study

    Statins may increase life of diabetics: Study
    The use of cholesterol-lowering statins may help prolong the lives of people with diabetic cardiovascular disease, says a new research.

    Statins may increase life of diabetics: Study