Close X
Sunday, November 24, 2024
ADVT 
Health & Fitness

Nicotine in e-cigarettes raises chronic bronchitis risk: Study

Darpan News Desk IANS, 07 Jun, 2019 06:57 PM

    E-cigarette vaping with nicotine not only hampers mucus clearance from the airways, but also increases the risk of chronic bronchitis, warn researchers.

    A single session of vaping can deliver more nicotine in the airways than smoking one cigarette, warned researchers in a study published in the American Journal of Respiratory and Critical Care Medicine.

    "The question was whether vape containing nicotine had negative effects on the ability to clear secretions from the airways similar to tobacco smoke," said Matthias Salathe, senior author of the study and Professor at the University of Kansas.

    The study's findings showed that vaping with nicotine impaired ciliary beat frequency, dehydrates airway fluid and made mucus more viscous or sticky.

    These changes make it more difficult for the bronchi, the main passageways to the lung, to defend themselves from infection and injury.

    "Vaping with nicotine is not harmless as commonly assumed by those who start vaping. At the very least, it increases the risk of chronic bronchitis," Salathe said.

    The researchers observed that exposing human airway cells to e-cigarette vapour containing nicotine resulted in a decreased ability to move mucus or phlegm across the surface. This phenomenon is called "mucociliary dysfunction."

    Mucociliary dysfunction is a feature of many lung diseases, including asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis.

    For the study, the researchers tested the effects of nicotine-containing e-cigarette vapours on airway mucociliary function in differentiated human bronchial epithelial cells (HBECs) and sheep, whose airways mimic those of humans when exposed to e-cigarette vapour.

    The researchers concluded that nicotine produced these negative effects by stimulating the ion channel transient receptor potential ankyrin 1 (TRPA1). Blocking TRPA1 reduced the effects of nicotine on clearance in both human cells in culture and in the sheep.

    MORE Health & Fitness ARTICLES

    Manipulative parents leave kids in distress later

    Manipulative parents leave kids in distress later
    Teenagers whose parents exert more psychological control over them have more problems establishing friendships and romantic relationships later, found a study....

    Manipulative parents leave kids in distress later

    Exercise the right way!

    Exercise the right way!
    It's important to take precautions while exercising as it can lead to significant damage to the muscles and the joints. Let's find out what moves exactly are doing this....

    Exercise the right way!

    How to create the perfect sleep environment

    How to create the perfect sleep environment
    A good night's sleep is vital for your health and well being. From keeping away distractions from your bedroom to maintaining the right temperature, an expert...

    How to create the perfect sleep environment

    Let your mind wander to boost mental performance

    Let your mind wander to boost mental performance
    Engaging brain areas linked to so-called "off-task" mental activities such as mind-wandering and looking back at good times can actually boost performance....

    Let your mind wander to boost mental performance

    How body regulates weight loss

    How body regulates weight loss
    A hormone seen as a popular target to develop weight-loss drugs works by directly targeting the brain and triggering previously unknown activity in the nervous...

    How body regulates weight loss

    How to avoid weight gain this festive season

    How to avoid weight gain this festive season
    Worried about weight gain during festive season? Here are some healthy tips to bail you out....

    How to avoid weight gain this festive season