Close X
Saturday, November 23, 2024
ADVT 
Health & Fitness

Nicotine in e-cigarettes raises chronic bronchitis risk: Study

Darpan News Desk IANS, 07 Jun, 2019 06:57 PM

    E-cigarette vaping with nicotine not only hampers mucus clearance from the airways, but also increases the risk of chronic bronchitis, warn researchers.

    A single session of vaping can deliver more nicotine in the airways than smoking one cigarette, warned researchers in a study published in the American Journal of Respiratory and Critical Care Medicine.

    "The question was whether vape containing nicotine had negative effects on the ability to clear secretions from the airways similar to tobacco smoke," said Matthias Salathe, senior author of the study and Professor at the University of Kansas.

    The study's findings showed that vaping with nicotine impaired ciliary beat frequency, dehydrates airway fluid and made mucus more viscous or sticky.

    These changes make it more difficult for the bronchi, the main passageways to the lung, to defend themselves from infection and injury.

    "Vaping with nicotine is not harmless as commonly assumed by those who start vaping. At the very least, it increases the risk of chronic bronchitis," Salathe said.

    The researchers observed that exposing human airway cells to e-cigarette vapour containing nicotine resulted in a decreased ability to move mucus or phlegm across the surface. This phenomenon is called "mucociliary dysfunction."

    Mucociliary dysfunction is a feature of many lung diseases, including asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis.

    For the study, the researchers tested the effects of nicotine-containing e-cigarette vapours on airway mucociliary function in differentiated human bronchial epithelial cells (HBECs) and sheep, whose airways mimic those of humans when exposed to e-cigarette vapour.

    The researchers concluded that nicotine produced these negative effects by stimulating the ion channel transient receptor potential ankyrin 1 (TRPA1). Blocking TRPA1 reduced the effects of nicotine on clearance in both human cells in culture and in the sheep.

    MORE Health & Fitness ARTICLES

    Calorie-restricting diets slow ageing

    Calorie-restricting diets slow ageing
    Having diets with fewer calories may help you delay ageing and age-related disorders such as memory loss, finds new research....

    Calorie-restricting diets slow ageing

    How to make kids eat healthy food in school

    How to make kids eat healthy food in school
    Along with the menu, improving the environment of the school cafeteria is important to ensure intake of healthy food by children, says a new research....

    How to make kids eat healthy food in school

    Home cooked food, the ideal recipe for healthy diet

    Home cooked food, the ideal recipe for healthy diet
    Those who frequently cooked at home -- six-to-seven nights a week -- also consumed fewer calories on the occasions when they ate out, the findings showed....

    Home cooked food, the ideal recipe for healthy diet

    Emotional stress affects young women's heart more

    Emotional stress affects young women's heart more
    Young women with heart diseases are more likely than men to have reduced blood flow to their heart if they are under emotional stress, says a new research....

    Emotional stress affects young women's heart more

    Travelling with a smoker increases cancer risk

    Travelling with a smoker increases cancer risk
    While simply sitting in cars with people who smoke, non-smokers breathe in a host of potentially dangerous compounds that are associated with cancer, heart disease...

    Travelling with a smoker increases cancer risk

    Filtered coffee keeps diabetes at bay

    Filtered coffee keeps diabetes at bay
    Regular, moderate consumption of filtered, decaffeinated coffee may decrease an individual's risk of developing Type 2 diabetes, promising research indicates....

    Filtered coffee keeps diabetes at bay