Close X
Saturday, November 23, 2024
ADVT 
Health & Fitness

Nicotine in e-cigarettes raises chronic bronchitis risk: Study

Darpan News Desk IANS, 07 Jun, 2019 06:57 PM

    E-cigarette vaping with nicotine not only hampers mucus clearance from the airways, but also increases the risk of chronic bronchitis, warn researchers.

    A single session of vaping can deliver more nicotine in the airways than smoking one cigarette, warned researchers in a study published in the American Journal of Respiratory and Critical Care Medicine.

    "The question was whether vape containing nicotine had negative effects on the ability to clear secretions from the airways similar to tobacco smoke," said Matthias Salathe, senior author of the study and Professor at the University of Kansas.

    The study's findings showed that vaping with nicotine impaired ciliary beat frequency, dehydrates airway fluid and made mucus more viscous or sticky.

    These changes make it more difficult for the bronchi, the main passageways to the lung, to defend themselves from infection and injury.

    "Vaping with nicotine is not harmless as commonly assumed by those who start vaping. At the very least, it increases the risk of chronic bronchitis," Salathe said.

    The researchers observed that exposing human airway cells to e-cigarette vapour containing nicotine resulted in a decreased ability to move mucus or phlegm across the surface. This phenomenon is called "mucociliary dysfunction."

    Mucociliary dysfunction is a feature of many lung diseases, including asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis.

    For the study, the researchers tested the effects of nicotine-containing e-cigarette vapours on airway mucociliary function in differentiated human bronchial epithelial cells (HBECs) and sheep, whose airways mimic those of humans when exposed to e-cigarette vapour.

    The researchers concluded that nicotine produced these negative effects by stimulating the ion channel transient receptor potential ankyrin 1 (TRPA1). Blocking TRPA1 reduced the effects of nicotine on clearance in both human cells in culture and in the sheep.

    MORE Health & Fitness ARTICLES

    App to insult you into losing weight

    App to insult you into losing weight
    If you have set your sight on losing weight, here is a calorie-counting app that insults you for all the extra calories you consume in a day....

    App to insult you into losing weight

    Nicotine digestion shows best method to kick the butt

    Nicotine digestion shows best method to kick the butt
    Paving the way for tailor-made treatments to stop smoking, researchers have shown that finding out how quickly smokers break down nicotine in their bodies is the key to helping them quit....

    Nicotine digestion shows best method to kick the butt

    Allergic to nuts? Know how much is too much

    Allergic to nuts? Know how much is too much
    Researchers have identified the level of five of the most common food allergens which would cause a reaction in the most sensitive 10 percent of people....

    Allergic to nuts? Know how much is too much

    Eating almonds decreases belly fat

    Eating almonds decreases belly fat
    Including almonds in your daily diet could help reduce belly fat, a well-established heart disease risk factor, says a study.

    Eating almonds decreases belly fat

    Flu Season Is Peaking In Many Parts Of Canada; The Sick Should Head To Bed

    Flu Season Is Peaking In Many Parts Of Canada; The Sick Should Head To Bed
    Health authorities were warning all fall that this could be a bad flu season, because of the type of virus that is most commonly infecting people and the fact that this year's flu vaccine doesn't offer optimum protection against it

    Flu Season Is Peaking In Many Parts Of Canada; The Sick Should Head To Bed

    Trying For Test-tube Baby? Moms' Risks Are Rare, Include Over-stimulating Ovaries

    Trying For Test-tube Baby? Moms' Risks Are Rare, Include Over-stimulating Ovaries
    CHICAGO — Complications are uncommon for women undergoing test-tube fertility procedures: A new 12-year U.S. study shows the most frequent involve drugs used to stimulate ovaries, but it suggests problems are rarely fatal.

    Trying For Test-tube Baby? Moms' Risks Are Rare, Include Over-stimulating Ovaries