Close X
Thursday, October 31, 2024
ADVT 
Health & Fitness

Nicotine in e-cigarettes raises chronic bronchitis risk: Study

Darpan News Desk IANS, 07 Jun, 2019 06:57 PM

    E-cigarette vaping with nicotine not only hampers mucus clearance from the airways, but also increases the risk of chronic bronchitis, warn researchers.

    A single session of vaping can deliver more nicotine in the airways than smoking one cigarette, warned researchers in a study published in the American Journal of Respiratory and Critical Care Medicine.

    "The question was whether vape containing nicotine had negative effects on the ability to clear secretions from the airways similar to tobacco smoke," said Matthias Salathe, senior author of the study and Professor at the University of Kansas.

    The study's findings showed that vaping with nicotine impaired ciliary beat frequency, dehydrates airway fluid and made mucus more viscous or sticky.

    These changes make it more difficult for the bronchi, the main passageways to the lung, to defend themselves from infection and injury.

    "Vaping with nicotine is not harmless as commonly assumed by those who start vaping. At the very least, it increases the risk of chronic bronchitis," Salathe said.

    The researchers observed that exposing human airway cells to e-cigarette vapour containing nicotine resulted in a decreased ability to move mucus or phlegm across the surface. This phenomenon is called "mucociliary dysfunction."

    Mucociliary dysfunction is a feature of many lung diseases, including asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis.

    For the study, the researchers tested the effects of nicotine-containing e-cigarette vapours on airway mucociliary function in differentiated human bronchial epithelial cells (HBECs) and sheep, whose airways mimic those of humans when exposed to e-cigarette vapour.

    The researchers concluded that nicotine produced these negative effects by stimulating the ion channel transient receptor potential ankyrin 1 (TRPA1). Blocking TRPA1 reduced the effects of nicotine on clearance in both human cells in culture and in the sheep.

    MORE Health & Fitness ARTICLES

    Stay Fit, Stay H‘app’y

    Stay Fit, Stay H‘app’y
    We’ve listed the top-recommended and trending apps & gadgets in the health and fitness industry that can help you keep a track on your exercising goals.

    Stay Fit, Stay H‘app’y

    A Night-time Stroll

    A Night-time Stroll
    Sleepwalking is a behavioural sleep disorder most often affecting children. As its name suggests, sleepwalking involves walking around or performing other actions while sleeping.

    A Night-time Stroll

    A Couple's Guide to Infertility

    A Couple's Guide to Infertility
    Not many are aware that infertility is a common issue among couples in Canada. According to Infertility Awareness Association of Canada (IAAC), one in six Canadian couples struggles to conceive. This problem can range from being unable to conceive to having difficulties bearing children.

    A Couple's Guide to Infertility

    Aquacise To Get Fit This Summer

    Aquacise To Get Fit This Summer
    If you are looking to create a healthier lifestyle, but are not a fan of working out, aqua fitness may be for you. 

    Aquacise To Get Fit This Summer

    Your Recommended Daily Dose

    Your Recommended Daily Dose
    What you need to know about vitamins and their benefit to your body!

    Your Recommended Daily Dose

    Mind Your Food

    Mind Your Food
    Re-evaluating our responses to food

    Mind Your Food