The caption is directed to online "trolls" who she says write "unkind things." She writes, "This is how I look. I feel happy" before adding that she thinks she looks "strong and healthy."
Slamming body critics is nothing new for Schumer. She told Glamour magazine it was "not cool" in another Instagram post last month for mentioning her in an issue focused on plus size fashion.
She wrote that there's nothing wrong with being plus-size, but disputed having a plus-size body, suggesting that labeling her body type that way could have a negative influence on young girls.
Actors Leonardo DiCaprio and Idris Elba won the big honours at the 22nd Screen Actors Guild (SAG) Awards, which focussed on diversity amongst winners, especially in the wake of the Oscars controversy.
Late singer David Bowie has reportedly left a half of his $100 million estate to his wife Iman, along with the couple's home on Lafayette Street in Manhattan, according to his will filed in a court.